Antibody

Antibody

Home - Category: Uncategorized (Page 2)

Category: Uncategorized

Antisperm Antibodies

Posted on September 1, 2018 in Uncategorized

There are many causes and reasons for infertility in males, of which one of them is antisperm antibodies. A man suffering from antisperm antibodies generally gets sensitized to sperm, to cause an immune system that destroys the sperms found in the body.

In a normal man, a barrier in his testes protects the sperm from the immune system. However, those men with antisperm antibodies have a broken barrier wherein immune cells can easily access the sperm. With the unique antigen surface that is found on such sperms, the immune system detects its presence and thus triggers a response.

About 10% of infertile men suffer from antisperm antibodies and this is what interferes with the quality and function of the sperm. It is depending on the location of the antibodies that the sperm is affected. If the antibodies are on the tail, then the sperms are either immobilized or found clumped together. If they are found on the head, then the sperm is prevented from binding to the egg, and thus prevents fertilization from taking place.

There are various causes for antisperm antibodies developing, of which the main reason is the cervical mucus found in some woman. This cervical mucus tends to develop antibodies in the sperm and is the cause of about 40% of the unexplained infertility in couples. Even anything that disrupts the barrier found between the sperm and immune system like infection, injury to the testicles and twisting of testicles can lead to antisperm antibodies.

Other causes of antisperm antibodies are undescended testicles, testicular biopsy and cancer, varicocele and congenital absence of vas deferens. About 70% of men who had a vasectomy reversal have also been found to have antisperm antibodies.

Doctors can easily diagnose antisperm antibodies with an analysis of the man’s sperm and by analyzing the woman’s cervical mucus after sex for any antibodies. However, when diagnosed with antisperm antibodies, it is not easy to eliminate the antibodies. High doses of cortico steroids generally lower the number of antibodies to restore fertility temporarily. However, these high doses bring with it many serious side effects.

This is the reason couples who suffer from this condition usually turn to assisted reproductive technologies to conceive a baby. One of the techniques used here is washing the sperm before in vitro fertilization. With this, the sperm can produce fertilized eggs better for implantation. Sometimes, washing of the sperm is also used in intrauterine insemination.

What You Need to Know About Sperm Antibodies

Posted on August 24, 2018 in Uncategorized

20% of all cases of infertility are due to mutual infertility, and 20% due to unexplained infertility. Combined, that’s nearly half of all the cases of infertility!

If the woman is ovulating, doesn’t have blocked tubes, hormonal imbalances or other reproductive system conditions, and, the man has normal sperm parameters, what’s the problem?

Why can’t they get pregnant?

1. Presence of sperm antibodies
2. Toxic mucus
3. Food intolerances

The first test you should consider is a post-coital test. This test will show how many sperm are still alive after intercourse in the woman’s reproductive system.

If the woman has sperm antibodies in her mucus, or has overly acidic mucus due to toxin overload in the body then the sperm will not fare well and their minutes (not days) will be numbered.

Channels of elimination

You see, your body will rely on all possible channels of elimination when it comes to getting rid of toxins. They are mostly mucus and discharge producing organs such as the nose, lungs, skin, kidneys, gut, vagina and penis.

This is where detoxing comes into the picture. Each couple, regardless of whether you are infertile or not should consider detoxing before conception.

Heavy metals exposure has a detrimental impact on the immune system, especially on autoantibody production which can lead to infertility in susceptible individuals. One study found that patients with mercury allergy had more antisperm antibodies than patients without the mercury allergy. (Neuro. Endicronol. Lett. 2005)

Food intolerances and sperm antibodies

If the immune system is in overdrive (due to constant exposure to food you are intolerant to) it can adversely react to your partner’s sperm and /or fertilized egg and destroy it. This can lead to creation of antibodies to your partner’s sperm and can predispose you to miscarriages and still births.

In the case of food intolerances you will not necessarily know you’ve got one until you do a proper blood test or you simply eliminate the food from your diet and wait to see if the symptoms go away. It can take up to 3 months for the immunocomplexes (antibody and antigen sticking together) to clear from your system.

Our body is one closed circuit. Everything that enters your body: through air that you breathe, food and drinks you consume or lotions and potions you rub on your skin will affect every single cell in your body! It all ends up in your blood. Your blood carries it though kilometers of blood vessels from the biggest aorta to the tiniest capillaries barely visible to the eye. Just think about that, for a second.

And the next time you want to consume something you know is not healthy just remember the closed circuit and know that it won’t just come out without leaving any damage behind.

Sperm Antibodies in the mucus

If the woman’s mucus contains sperm antibodies, more than just a detox is required. Studies have shown that women can develop antisperm antibodies if sperm has come into contact with the mucosal or systemic immune system. This can happen if there are minor wounds in the vagina, rectum or the oral cavity. Sperm antibodies in cervical mucus cause the heads of the sperm to stick to the cervical mucus.

To treat sperm antibodies in the mucus you’ll need to use condoms for 3-6 months while the woman’s immune system is addressed with diet, nutritional supplements, herbs and other complementary medicine treatments as required.

During the 3-6 month period, because the woman didn’t come into contact with the sperm, the present antibodies to sperm will be broken down and no new ones will be produced.

This is also a very beneficial time to learn about timing your most fertile days!

Then you remove the condom and have intercourse at the most fertile time to conceive. This will not allow enough time for your body to produce new antibodies. Also after having your immune system treated and retrained during those 3-6 months it is likely that your immune system would not react again.

If the woman has sperm antibodies in her blood and not just the mucus, than just relying on the condom will not be enough and a longer immune system treatment may be required.

Men can have sperm auto antibodies

Autoimmunity results from the abnormal immune response against the body’s own tissue. Men can develop antibodies against their own sperm. This can cause the sperm to agglutinate (or stick together) or cause the tails of the sperm to stick to the cervical mucus.

Autoimmunity of any kind often derives from childhood or even earlier development in the womb. If the mother was consuming foods she was intolerant to during her pregnancy, then her antibodies influenced what type of immune system dominance the child will have.

The immune system is fascinating in that it needs to learn the ropes. Unlike the other cells in the body it intimately interacts with our environment everyday.

If you have an inflamed gut, due to a bacterial or parasitic infection or as a result of food intolerance, large molecules from food will enter the sterile environment behind the gut, through the gaps between the cells. Once they are in the area of the body they are not meant to be in, the immune system will pick them up and treat them as invading pathogens. Now that the immune system has been exposed to this substance once, it’ll produce a whole army of antibodies against this food. So now each time you eat this food, they’ll attack. Overtime this will exhaust the immune reserve, making it less robust when it comes to bacteria, viruses and cancers and more hypersensitive to its own tissue and innocuous substances such as pollen and food.

This starts a viscous cycle if the food intolerance is not picked up upon and treated naturopathically.

If as a child you were not breastfed, than you may have missed out on your mother’s antibodies and this may have predisposed you to an immune system that is overly reactive. If, on the other hand you mother has many allergies, then you can consider yourself lucky for not having been breastfed.

Also if you grew up in a super clean and sterile environment, your immune system didn’t have any bugs to learn from. Some childhood diseases and contact with dirt as a kid are very beneficial for the immune system. They teach your immune system what sort of antibodies it should be producing, so it’s less likely to attack food molecules or your own tissue.

The good news is that the immune system can be retrained in three easy steps;

1. Remove the triggers for 3-6 months or longer, depending on the severity.
2. Heal the inflammation and the mucosal surfaces, with the right nutrients and diet.
3. Treat the immune system with adequate protein intake, a clean and pure diet, nutritional supplements, probiotics and herbs. Key nutrients to consider are vitamin C, zinc, selenium, vitamins E and A (or betacarotene), omega 3, and herbs such as Panax ginseng, Echinacea, Hemidesmus, Astragalus, Withania and Saw palmetto.

In this article we looked the causes of sperm antibodies and touched on unexplained infertility as it relates to food intolerances. There are plenty of other environmental influences that can contribute to unexplained infertility. Natural fertility treatment for sperm antibodies consists of abstinence from the triggers, dietary and lifestyle adjustments and nutritional and herbal support for the immune system. Once you truly grasp the interconnectedness of all body systems you’ll understand why and how what you eat, drink and breathe can make all the difference to your fertility.

Want to Have a Candida Antibodies Test With ImuPro?

Posted on August 18, 2018 in Uncategorized

Candida antibodies tests are necessary to determine if the body needs any external medications to recover from fungal infection. The pathogen has the ability to self-stabilise itself and not allow the gut microbiota to recover and re-establish the normal metabolic environment. It consolidates its position in the digestive tract and further damages the inner lining resulting in the release of food and other particles into the blood stream. The leaked gut is the primary reason for food intolerance and build-up of gas and subsequent complications.

The type of treatment to be prescribed depends on finding how the body’s immune system is tackling the problem. Measuring the presence of immunoglobulin proteins such as IgG in the gut flora help establish the answer to this question and ascertain the treatment measures to be taken to address the proliferation. A chronic case such as Candidiasis where the fungi has permeated into the mucosal tissues increases the level of IgA, IgG and IgM antibodies. In such instances, their levels are found to be considerably higher than what would have been under normal circumstances.

All Candida related antibody and antigen tests should be checked by a practising physician and evaluated in relation to the person’s medical history. As in the case of all tests, the results are dependent on various factors such as past infections, the presence of the protein in the affected tissues and many more. For instance in the case of IgG, the tests would not be positive in case the person is suffering from illness and already has a high incidence of the antibodies in his serum. In certain cases, the IgG may persist several years after the infection has been completely eradicated. This is mostly due to the immunoglobulin’s ability to persist for a long period of time.

IgA is predominant in the mucosal tissues though it represents less than 20% of the proteins found in the human serum. A high incidence of IgA can be associated with mucosal epithelial, tracheobronchial, and genito-urinary infections of Candida. IgM is found in the intravascular cells and is the predominant immunoglobulin in early infections. Later illnesses may show a lesser level of this antibody as compared to the earlier ones. Besides these testing that may or may not prove a positive, antigen checks help determine if the proliferation has overwhelmed the gut flora. The presence of Candida antigen in the serum is a very positive indicator that the fungi has already entrenched itself in the gut. However, the absence of the antigen is an indeterminate result and cannot be taken as a positive sign that indicates the absence of the pathogen.

An ImuPro test helps to find all the allergies that affect patients. ImuPro tests analyse the patient’s reaction to over 271 food varieties and help clearly define the sources of any allergy.

Top