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Category: Uncategorized

Laughter – The Natural Antibody That Burns Calories

Posted on October 14, 2018 in Uncategorized

For some people who want to stay healthy without getting tired of doing hard exercises or spending a lot of money on medicine, laughing may be the alternative activity they have to choose.

Laughing is almost the same as aerobics exercise, which benefit especially the upper part of the body. It is a work out for diaphragm, abdominal, respiratory, facial, shoulders, back muscles and even legs. Moreover, it makes digestion and absorption system functioning better. According to some studies, laughter can burn calories equal to walking or biking.

A study conducted at Vanderbilt University demonstrated that 10 to 40 percent calories are burnt through 10 to 15 minutes laughing. In fact, new research published in the International Journal of Obesity said that laughing is the best medicine for a weight problem.

One thing for sure, laughing needs no cost all. It is a natural antibody or in other words priceless medicine. The same as smiling which can increase endorphin hormone, so as laughing can strengthen the immune system and increase natural killer cell levels that prevent the growth of cancer cells. Laughing also makes a person’s body more relaxed and thereafter reduces problems related to high blood pressure, heart attack or stroke, depression, anxiety, stress, arthritis, and ulcer.

Most of the time, laughing is also an exercise for the heart and lungs. It can increase the amount of oxygen getting through our body. Thus, laughter is believed to stimulate both sides of brain and enhance the brain function related to retaining information and solving problem.

Believe it or not, children laugh more than adult. This is pathetic because adult is the one who has more problems. That is why they need more laughter to overcome them. Or is it because they laugh less thus they have more problems?

Custom Antibody Sequencing – Discovery of the Century

Posted on October 8, 2018 in Uncategorized

Brief introduction to Custom antibodies

Antibodies help us to protect from numerous bacterial infections. They are big protein compounds white cells. Custom antibodies are distinctive proteins which are separated from the analysis subject’s blood when a particular disorder or foreign compound is inserted into its structure. Initially, custom antibodies were described in studies carried by experts in early 1980s. To accelerate to express Charles Darwin’s concept of evolution, editors of New Scientist Magazine, John Gribbin and Jeremy Cherfas, introduced an impressive technique to research the human development. They produced a blood serum protein and inserted it into a rabbit. The entire body of the rabbit identified the foreign proteins and created antibodies – which were particular to unique proteins. You will find many companies which develop custom antibodies and provide high-end services like transient expression or antibody sequencing for scientists who are trying to understand and explore vaccines for various health issues. Recognized as custom antibody solutions, these agencies generally get samples of the foreign element and the subject’s serum or blood. The foreign element is recognized as an antigen and the antibodies are proteins which combine with them.

Antibody sequencing and transient expression at a glance

Many companies exist today which deals with protein sequencing and sequencing dead hybridomal cells. The researchers which want to boost their process of innovation and support, approaching such companies that deal with transient expression is the right option. Today, the antibody sequencing is performed over different species like rat, mouse, human guinea pig, hamster, bovine, rabbits and human antibody concealing EBV cell lines. Most of the companies which are into the antibody development business maintain the highest standards and follow projected timelines.

Transient expression of a transformed gene in the preferred target cells over the comparatively short time period; and doesn’t always show integration of a gene into the host chromosome and isn’t transferred to the following generation. For the fast and quick formation of cell lines indicating full-length recombinant antibodies and completely improved antibodies, modern science has introduced enhanced technology.

For the period of the transient expression, the protein is indicated just for a short time, that is perfect for confirmation of theory because the DNA which is released in the transfection procedure is generally not involved into the nuclear genome and is going to be diluted via degraded or mitosis. When the scientist has recognized the subjected protein of interest, the development of a balanced transfected cell line is the expected second step that needs the transfected gene to live in cells’ genome. This takes more time compared to transient transfections to get the stable transfection. The multi-simultaneous testing method uses numerous proprietary vector models for increasing the development of recombinant protein you need. After that, the Bioinformatics is performed for creating best suited proteins required for specific studies.

Following the same, there are many companies these days which deals with transient expression and antibody sequencing as well as helps in challenging projects like DNA sequencing, drug development, cloning, patent application, etc. Today, the advanced antibody development plays a vital role in helping human beings fight against insoluble disease and treat the patients.

Long Term Space Flight and Human Biosystem Antibodies – Deal Breaker or Is There a Solution?

Posted on September 30, 2018 in Uncategorized

NASA’s Astrobiological division certainly has some bugs to work out, literally with long-term human spaceflight. If we are going to create 100-years spaceship, and boldly travel to places that no human has ever been, then obviously we need to keep those humans alive for the duration of that trip. There are so many challenges involved it seems a bit overwhelming, but maybe it’s not, maybe we just aren’t thinking this through properly. Yes, we have the best minds in the business working on it, but maybe they aren’t thinking outside the box anymore.

Now then, there are those that work in NASA and have been working on these things for decades, and that last statement might almost be a slap in the face to their hard work. I don’t doubt for a second that they have learned all kinds of wonderful things, things which have not only helped the space program, but things which are also saving lives here on earth in the healthcare industry. Any time we do this sort of research, we learn more about the human body, and the human biosystem.

There was an interesting article in SpaceDaily – Your Portal to Space” which was filed under the category of; Space Medicine, and article was titled; “Antibody Production Gets Confused During Long-Term Spaceflight,” by Staff Writers in Bethesda, MD published on May 20, 2011. The article stated;

“Antibodies produced in space are less effective than those produced on terra firma. Reduced effectiveness of antibodies makes astronauts more susceptible to illness, while increasing the danger posed by bacteria and viruses likely to coexist with wayfaring astronauts.”

Obviously, a weakened immune system is a real problem in space, much more than it is here on Earth. What the researchers found was that “the antibodies generated by the group immunized in space was decreased. The spaceflight conditions alter the immune system and its ability to protect against infections and tumors, posing a serious risk for astronauts.”

Okay so, let me throw out some thoughts here if I might specifically, “WHAT IF” – yes, I know big words, but what if the anti-body production in long-term space flight had to do with light, circadian rhythm, and the Earth’s frequency? What if those exact conditions were exactly mimicked during long term space flight, along with some artificial gravity scheme?

Yes, these are the questions I believe we need to address when it comes to long-term space flight. Most are, but when it comes to this particular problem, it seems these are things we should be asking ourselves.

What about the human innate evolutionary bonding to the extremely low frequencies of planet Earth, the planet has a specific resonance too. Surely, the human biosystem along with all its symbiotic relationships will work better and correctly if they are shielded from the radiation and have available the optimized conditions they’ve evolved with. Please consider all this and think on it, let’s get this problem solved so we can von voyage to distant stars.