Antibody

Antibody

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Month: April 2018

Prostate Cancer Antibody – Promising Treatment For Your Cancer

Posted on April 9, 2018 in Uncategorized

A number of researchers have revealed an antibody which will bond with prostate cancer tissue and instigate direct cell death while injected into mice. The discovery would nearly be a treatment to cancer of prostate if outcomes carry over to humans.

It is one of the principal diseases frightening men nowadays. The cancer is #2 on the listing of most widespread cancers in men. More than the past 150 years lots of various treatments have been developed as part of research for prostate cancer treatment.

The study published in PNAS {the Proceedings of the National Academy of Science} stated that the antibody, called F77, was discovered to bond more readily with tissues and cells of cancerous prostate than with benign tissue and cells, and to help the death of cancerous tissue.

Even so, the study showed that it did not be intended for normal tissue or tumor tissues in other areas of the body including the colon, kidney, pancreas, skin cervix, lung, or bladder.

Researchers wrote the antibody “proves promising potential for diagnosis and treatment of the cancer, particularly for androgen-independent metastatic prostate cancer,” which frequently extends to the bones and is not easy to treat.

Antibodies are also already being employed to deal with diseases like lymphoma and breast cancer. It is said that until now there has been no successful antibody therapy for cancer of prostate. However, any research team has produced an antibody named F77 which looks so potential. In spite of the research being at a very early step, it brings up the hope of an effectual treatment for advanced prostate cancer.

What are Antibodies

Posted on April 3, 2018 in Uncategorized

Antibodies, also called immunoglobulins are large y-shaped proteins which function to identify and help remove foreign antigens such as viruses and bacteria.

In mammals there are five main types of antibodies including: IgA, IgD, IgE, IgG, and IgM. There are 4 IgG and 2 IgA subtypes present in humans.

Antibodies are created by plasma cells which are derived from the B-cells in the immune system. Due to the fact that antibodies exist freely in the bloodstream or bound to cell membranes, they are said to be part of the humoral immune system.
Every different antibody recognizes a specific foreign antigen. This is because the two tips of its “Y” are different to each antibody are allow different antibodies to bind to different foreign antigens. When the antibody binds to a bacteria, it tags the microbe or virus for attack by the immune system such as killer T-cells. Sometimes, antibodies can directly neutralize the foreign body. The production of antibodies by B-cells is the main function of the humoral immune system.

Autoimmune disorders can usually be traced to antibodies which bind the body’s own proteins or epitopes, and these types of antibodies can be detected through serological blood tests. Due to the amazing specificity of antibodies, they have some important practical applications in both medicine for the detection of HIV and other viruses in blood, and in research to purify and detect proteins in the study of molecular biology. For example, currently medicine is using biotechnologically designed monoclonal antibodies which work as an antibody therapy. These methods are being employed recently and are the result of numerous clinical trials in a number of diseases including cancer, and rheumatoid arthritis.