Idiopathic Thrombocytopenic Purpura – Is Anti-D Antibody the Right ITP Treatment For You?

Posted on June 17, 2018 in Uncategorized

One form of ITP treatment is Anti-D Anti-body. This is just one of the conventional medical treatments doctors prescribe for idiopathic Thrombocytopenic Purpura (an autoimmune disease where the body destroys it’s own blood platelets. Marketed under the names of WinRho SDF or Rhophylac, Anti-D Antibody is a blood product used to raise the blood platelet count temporarily and occasionally longer term. In one study it was found to be effective about 80% of the time although the effects were temporary. the effects usually last about a month. Just what is Anti-D you might ask?. It is a freeze dried gamma globulin fraction which contains antibodies to Rh (D). It is made of human plasma from a limited list of donors. The plasma undergoes a viral inactivation and micro filtering process using a solvent detergent.

The donors are stimulated to produce Immunoglobulin with high levels of specific antibodies, thereby reducing the cost of the treatment by at least half of what IVIg treatment would cost. It is also safer to use then IVIg , because Anti-D has been treated to inactivate any form of viral contamination. Because Anti-D antibodies and action are so specific, it is only effective for people who still have their spleen and are Rh positive (about 85% of population). It may not be suitable for some pregnant women. Anti-D Antibody is taken either through an IV drip, which usually takes about half an hour or through an IV push, which just as the term indicates, pushes the infusion through your blood stream in about 5 minutes. These treatments can be given as a single dose or 2 doses over separate days. The frequency and dose is determined by the patient’s clinical response.

What are the side effects? Not pleasant to be sure and sometimes even deadly. They range from headaches, chills, fever and body aches, pain and swelling at the injection site. Not everyone experiences the same side effects. For people sensitive to blood products there is a remote risk of shock.. Anemia is also a problem because of the destruction of red blood cells. Monitoring the patient is especially important for people with low hemoglobin. Sometimes rare but serious complications such as intravascular hemolysis can occur which is releases hemoglobin into the plasma and involves pre-mature destruction of the red blood cells, and can result in death. Patients should be advised of warning signs for intravascular hemolysis such as back pain, shaking chills, fever, discolored urine, fluid retention, decreased urine, shortness of breath and sudden weight gain.

If you have ITP disorder and your physician has recommended Anti-D Antibody you should discuss all aspects of treatment with him, especially potential side effects in order to make the right decision about your health.

It seems like an awful lot of risk for a temporary fix. Don’t you think? Consider the risks and look for safer alternatives.

Peptic Ulcer Helicobacter Pylori – Breath And Antibody Blood Tests

Posted on June 9, 2018 in Uncategorized

Like the tissue test, the urea breath test makes use of the fact that H. Pylori secretes urease, which converts urea into ammonia, producing carbon dioxide as it does so. You are asked to eat nothing for 12 hours before a breath test and are then given a drink containing urea to which a tiny amount of perfectly safe radiation has been added. Thirty minutes later, a small breath sample is collected. If H. pylori is present in your stomach, the urea is converted into ammonia and carbon dioxide, which is then absorbed and excreted in your breath, along with a tiny amount of radioactivity. This can then be measured With a special machine in the hospital laboratory.

The advantage of the breath test is that it is very straightforward and takes a very short amount of time. Like the biopsy urease test, it is very accurate and confirms that you have active H. pylori infection present at the dine of the test. This also means that, if necessary, the breath test can be performed repeatedly to check whether the bacteria have been eradicated after treatment. The disadvantage of the test, like some other H. pylori tests, is that the result may be inaccurate if you are taking proton pump inhibitor medication. Also the result is not usually available for several days because of the measuring equipment used.

Antibody Blood Test

As with other infections, H. pylori infection trigger the production of specific antibodies in your blood. These can then be looked for with a simple blood test and the presence of these antibodies confirms H. pylori infection. Once your body has produced these antibodies they may persist for many years even after the infection has been eradicated.

For this reason, the blood test is useful for diagnosing infection only in a person who has never had H. pylori treatment, and it cannot be used more than once. The real advantage of the test is that it is very quick and usually available in the GP’s surgery. Unlike the other tests for H. pylori, any drugs that you may be taking do not influence the blood test.


Overcome Female Infertility – What is Antisperm Antibody Test?

Posted on June 2, 2018 in Uncategorized

As we mentioned in previous articles, infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to term. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist. In this article, we will discuss what male infertility antisperm antibody test is.

I. Definition
The antisperm antibody test is one of procedure which helps to see the antigens of the immune system function toward sperm invasion through blood test. If the immune system recognized or not the sperm as the foreign object, it will produces white blood cells to kill them.

II. Procedure
Blood is withdrawn from a vein in the arm of the infertile female in the clinic laboratory and is to analyzed by immunologic infertility specialist.

III. Diagnosis
The test uses a sample of sperm and adds a substance that binds only to the test sperm. Semen sample causes the immune system response in either the man’s or woman’s body. If there is an injure somewheres in the body or inflammation caused by irregular cell adhesion or implants such as endometriosis or sexual transmitted diseases infection which may stimulate the production of white blood. The white blood cells can damage or kill sperm if a high number of sperm antibodies is found leading to immunologic infertility.

Women may have an allergic reaction to her partner’s semen and make sperm antibodies leading to faultily recognizing the sperm as foreign invasion, thereby producing high a mount of antibody to kill them leading to infertility. This kind of immune response is not fully understood and happens only to small percentage of infertility couple. It is said that this kind of abnormal function can be treated by controlling the allergic reaction if the causes are found.